If we continue with the 4-2-2-2, the squad depth currently looks like this:
Fwd1: Rashford / Greenwood
Fwd2: Cavani / Ronaldo
LAM: Sancho / Pogba
RAM: Bruno / VdB
CM1: Fred / ??
CM2: McT / ??
LB: Telles / Shaw
RB: Dalot / AwB
CB: Bailly / Maguire
CB: Lindelof / Varane.
I think we've effectively replaced Pogba with Sancho. The backup LAM spot can go to one of the kids (Amad / Hannibal / Elanga).
I'm more worried about the CM spot. If one of McFred is injured, there's no one to take their place.
So no Martial, Mata or Matic in the squad now?