SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

I do feel like we are at the point where we just need to get as many people vaccinated and boostered as possible and just let the thing spread now (while protecting and shielding the vunerable).

I don't see how we can keep this up year after year otherwise because it's not going to just go away.

We can't keep what up exactly?

Vaccines and masks in limited circumstances and periods is hardly some huge societal pressure we can't sustain for a few years.
 
We can't keep what up exactly?

Vaccines and masks in limited circumstances and periods is hardly some huge societal pressure we can't sustain for a few years.

We can do vaccines and masks for as long as it takes and I should hope we do.

But the lockdowns, panic and general anxiety that this virus is causing globally is not healthy. It was necessary before the vaccines, but is it necessary now (genuine question as I don't know)?
 
Another day, another silly question from owlo.

Are those who are mrna vaccinated and had infection from Sars-Cov-1 succeptible to omicron?
 
Got my booster later this morning. My pregnant wife is booked in too.

I hope she’s ok after getting it - the tin foil hat posts re pregnant women have got under my skin and I feel a bit sick about it all.
Welcome to parenthood! Nothing but worries about your kid/s for the rest of your life. I'm sure you'll all be fine.
 
Another day, another silly question from owlo.

Are those who are mrna vaccinated and had infection from Sars-Cov-1 succeptible to omicron?

Yes. Although likely less susceptible than anyone else. The lab data on omicron has “hybrid immunity” (infection + vaccine) giving the best protection. Although still a long way below 100%.
 
My head is spinning again with all this vaccine spike protein evasion talk.

Do the vaccines work or not against this Omicron disease?
 
My head is spinning again with all this vaccine spike protein evasion talk.

Do the vaccines work or not against this Omicron disease?
It seems like it works pretty (maybe very?) well against severe disease, doesn’t look like it works very well in stopping transmission though.
 
A bit of a niche request, but any sort of data correlating to recovery times on those with omicron, vaxxed or otherwise? Just anecdotally speaking, I tested positive for the virus on Tuesday with the full board of symptoms (I'm doubled vaxxed with the Pfizer vaccine), but I've almost made a full recovery as of today. Some of my friends and family members also seem to be on the mend rather quickly too.
 
A bit of a niche request, but any sort of data correlating to recovery times on those with omicron, vaxxed or otherwise? Just anecdotally speaking, I tested positive for the virus on Tuesday with the full board of symptoms (I'm doubled vaxxed with the Pfizer vaccine), but I've almost made a full recovery as of today. Some of my friends and family members also seem to be on the mend rather quickly too.

Data from South Africa is that duration of illness is shorter than in previous waves.
 
Data from South Africa is that duration of illness is shorter than previous waves.
That's certainly encouraging. I assume that's for those who've built up immunity through a vaccination course and/or previous infection? Or is it agnostic of that?
 
That's certainly encouraging. I assume that's for those who've built up immunity through a vaccination course and/or previous infection? Or is it agnostic of that?

the doctor that first found it in South Africa was claiming no matter on vaccination or not the majority of cases were ok in a couple of days 5 max
 
Yes. Although likely less susceptible than anyone else. The lab data on omicron has “hybrid immunity” (infection + vaccine) giving the best protection. Although still a long way below 100%.

Interesting. So prior infection from SARS-COV2 offers better protection in tandem with the vaccines than prior infection from SARS-Cov1 ?
 
Interesting. So prior infection from SARS-COV2 offers better protection in tandem with the vaccines than prior infection from SARS-Cov1 ?

Correct.

Based on lab data with omicron. Needs to be confirmed with real life data before we can be certain.

EDIT: presume sars-cov-1 is a typo?
 


This is great to see. A small % of a very big number is still a big number but still…

Yep. I think a lot of countries including the UK would see that as great news, of it applies to them. The "yes, but" issues come round the specifics of course. In the UK the hospitalisation rate fell from around 8% of positive tests (early alpha) to about 2% with Delta. That seemed to be entirely a vaccination/immunity thing so we may already have had some/all of our big leap. In which case it's not good news for the UK at all.

Good news for countries like India of course, which had to cope with Delta with next to no vaccines and limited past immunity.

Incidentally, England will hit its (current rules) PCR test capacity end of this week/early next. Hopefully they'll change the rules to prioritise the right tests, rather than just let the system become completely logjammed and useless.
 
Yep. I think a lot of countries including the UK would see that as great news, of it applies to them. The "yes, but" issues come round the specifics of course. In the UK the hospitalisation rate fell from around 8% of positive tests (early alpha) to about 2% with Delta. That seemed to be entirely a vaccination/immunity thing so we may already have had some/all of our big leap. In which case it's not good news for the UK at all.

Good news for countries like India of course, which had to cope with Delta with next to no vaccines and limited past immunity.

Incidentally, England will hit its (current rules) PCR test capacity end of this week/early next. Hopefully they'll change the rules to prioritise the right tests, rather than just let the system become completely logjammed and useless.
How would they further narrow the prioritisation though? As far as I recall, the guidelines state that to be eligible for a PCR you should either display symptoms, have been in contact with someone who's tested positive, or you need one done for travel reasons. All of them seem pretty sensible criteria.
 
Yep. I think a lot of countries including the UK would see that as great news, of it applies to them. The "yes, but" issues come round the specifics of course. In the UK the hospitalisation rate fell from around 8% of positive tests (early alpha) to about 2% with Delta. That seemed to be entirely a vaccination/immunity thing so we may already have had some/all of our big leap. In which case it's not good news for the UK at all.

Good news for countries like India of course, which had to cope with Delta with next to no vaccines and limited past immunity.

Incidentally, England will hit its (current rules) PCR test capacity end of this week/early next. Hopefully they'll change the rules to prioritise the right tests, rather than just let the system become completely logjammed and useless.

True but SA have already gone through that with their second and third waves (also on graph)
 
This is giving me the same vibe as how I approached my exams at school wing it hope for the best and it turned out great!

Wouldn’t recommend it but that’s how the data reads.
 
How would they further narrow the prioritisation though? As far as I recall, the guidelines state that to be eligible for a PCR you should either display symptoms, have been in contact with someone who's tested positive, or you need one done for travel reasons. All of them seem pretty sensible criteria.
They also use them to check positive LFTs etc. LFTs aren't perfect but a LFT positive taken seriously is better than waiting for a late PCR. The contact bit is the other bit of the picture. If the observations are right about Omicron then the sheer volume of contacts will make it impossible to do the test quickly enough to do anything useful with the result.

The criteria are sensible but the tests are only useful at all if people can get a test as soon as they need it and can get the result the next day. We can do roughly 800k PCR tests/day - that's a huge number but not huge enough. Something has to give.

I know which bits I'd drop, but the NHS/public health lot will be doing a proper analysis of what they find most useful. Who knows, maybe we'll get lucky and it'll stop spreading before they have to choose.
 
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I got covid after being double vaxxed and lost my sense of smell/taste massively impaired. Within a week both were back.

I've heard of others who regained these senses very quickly, presumably due to having been vaccinated.
My girlfriend and I both had covid last summer and lost sense of smell/taste, hers came back after four days and mine after six days. This was before vaccines, obviously.
 
True but SA have already gone through that with their second and third waves (also on graph)
Sure, but their second to third waves only see a marginal improvement. We saw a massive improvement in the UK.

Still fingers crossed it'll be party hats all round next week.
 
Correct.

Based on lab data with omicron. Needs to be confirmed with real life data before we can be certain.

EDIT: presume sars-cov-1 is a typo?

No typo. I can’t remember where I was reading it, but a single mRNA dose combined with previous SARS-cov1 apparently produced the highest protection against older strains and antibody production compared to any other combination. (Something to do with binding to intake vectors of sarbecoviruses which tbh I didn’t understand. But they had minimal protection vs cov2 to start, but one mRNA dose really boosted it up past 2 dose levels on others )
 
Cancelled my christmas plans. We’ll do a family gathering in April.
 
Sure, but their second to third waves only see a marginal improvement. We saw a massive improvement in the UK.

Still fingers crossed it'll be party hats all round next week.

The SA picture is hard to understand alright. Why didn’t they get this same drop between waves 2 and 3? Is it because they didn’t get a decent level of population immunity until after delta hit?

So much speculation!
 
We can't keep what up exactly?

Vaccines and masks in limited circumstances and periods is hardly some huge societal pressure we can't sustain for a few years.

Don't you just love those halfwits who choose to wear their mask around their stupid chins....
 
Got my booster later this morning. My pregnant wife is booked in too.

I hope she’s ok after getting it - the tin foil hat posts re pregnant women have got under my skin and I feel a bit sick about it all.

"Should have waited for your first baby and then vaccinate" was my favourite comment wife and I got from our neighbour.
 
The SA picture is hard to understand alright. Why didn’t they get this same drop between waves 2 and 3? Is it because they didn’t get a decent level of population immunity until after delta hit?

So much speculation!

The obvious answer its milder considerably omicron but no one wants to say it just in case they are wrong.
 
I’d say we will be back to normal in the UK in March with the majority having built up immunity for further waves with the remaining majority, unfortunately, dead.

Just a thought though.
 
I’d say we will be back to normal in the UK in March with the majority having built up immunity for further waves with the remaining minority unfortunately, dead.

Just a thought though.
 
Somebody in the comments on that twitter thread is suggesting SA has a unique immunoprofile (learned that word from Twitter!) due to their high prevalence of beta variant before, which may be driving omicron to be less deadly there.
 
I’d say we will be back to normal in the UK in March with the majority having built up immunity for further waves with the remaining majority, unfortunately, dead.

Just a thought though.
Optimistic, I hope you are right. Given that approx 1/6th of the UK population over the full length of this pandemic have had covid and that very roughly 1 in 4 of those dont develop antibodies Im guessing it might take longer. Hope Im completely wrong.
 
Optimistic, I hope you are right. Given that approx 1/6th of the UK population over the full length of this pandemic have had covid and that very roughly 1 in 4 of those dont develop antibodies Im guessing it might take longer. Hope Im completely wrong.
You are wrong. I mean, it's been almost 2 years and you are still looking at reported cases.
 
Optimistic, I hope you are right. Given that approx 1/6th of the UK population over the full length of this pandemic have had covid and that very roughly 1 in 4 of those dont develop antibodies Im guessing it might take longer. Hope Im completely wrong.

I doubt a figure of 25% is remotely accurate. Where did you get that from?