I've heard from several places he will be dropping Mata and Fellaini and brining in Januzaj, Cleverley and Welbeck.
Hard to say if Rooney will play or be rested because of his toe?
I think it will be:
--------------------------DE GEA-----------------------------
VALENCIA---------JONES--------EVANS/SMALLING---------EVRA
---------------CLEVERLEY--------CARRICK---------------------
JANUZAJ----------------KAGAWA----------------------WELBECK
------------------------ROONEY-------------------------------
Maybe played n different positions but I think they will be the players on the pitch, maybe Fletcher instead of one of them, maybe kags or Rooney if he is rested.