Really apprehensive about this game and I think we will draw.
They are a side perfectly suited to playing us due to their high-octane pressing game and they were unfortunate to lose at Old Trafford last season - since then they have improved. Some of our most demoralising defeats in recent years have been to teams that either press the opposition high or play with a lot of intensity, such as Bilbao, Barcelona and City. Of course, Southampton don't compare to Barcelona, City and even what Bilbao were a few years ago, but it's not so much about their quality - even though they are a very good side - it's more so about their style of play.
We have very few really technically-gifted players or players who are comfortable under pressure and simply adept at retaining possession and keeping the tempo high. If we had every player at our disposal, the likes of Evans, Cleverley, Welbeck and obviously Carrick should be absolute shoe-ins for this game. Evans improves our composure and distribution from defence ten-fold and would be a calming influence in possession alongside Vidic. Welbeck is someone who always makes himself available to receive a pas with his movement and energy dropping deep and we will constantly need an open option tomorrow rather than being static in our play. Carrick is pretty self-explanatory really so there's no need to go into that.
Cleverley however will be a really big miss for us and despite a lot complaining about his contribution recently a lot of people will realise just how important he is tomorrow. Fellaini is quite clearly a good player to have up against a very combative midfield in Schneiderlin and Wanyama, but he doesn't display the same mobility, energy levels and effective ball-retention that Cleverley offers. He has to start in Cleverley's absence though, as Anderson and Giggs really do not inspire confidence in the middle of the park.
I would personally like to see Kagawa start as a number ten also, in place of Rooney or van Persie. Don't get me wrong, I am not a 'fanboy' or expecting a great performance from him every time he steps on the pitch, it's just we will need to progress up the pitch which more patience and fluidity to our game against Southampton. In many ways, he is a better link between the midfield and attack than Rooney and as shown against Sunderland we can often find ourselves struggling to link the midfield and attack as Rooney is naturally very attack-minded.
Other than that, I think Januzaj has to start and should be one of the first names on the teamsheet. Excellent form should always be rewarded by starting the following match, in Januzaj's case he also can't play in the Champions League midweek, so that's further case for inclusion. And Welbeck and Kagawa along with van Persie, who just might hit form after scoring during international week.