SARS CoV-2 coronavirus / Covid-19 (No tin foil hat silliness please)

Surge in cases among children in all states in the US now, according to weekly reports from American Academy and Pediatrics (AAP) and Children's Hospital Association (CHA).



I’m assuming this is because a lot of adults are vaccinated. You’d expect the proportion of kids getting sick to increase in that scenario.

Kids and covid seems to be the most politicised issue in the US right now. So it’s hard to see the wood for the trees. There also seems to be a big overlap with RSV admissions, which is muddying the waters a bit.

I’m sure @mav_9me know more about this than me though.
 
Maybe but that sort of defeatist talk stopped most countries even trying to.even seriously suppress covid, much less eliminate, which in turn directly resulted in the variants of concern.

I don’t think it’s defeatist. More pragmatic. Instead of putting life on hold pending an unattainable goal we need to immediately start preparing for a future where the virus is endemic. Particularly relevant in Australia right now.
 
Of course it’s mythical. I hadn’t realised the idea of herd immunity was still a thing. We’re 17 months in now and nutters are still talking about this as a possibility?
Let’s hope the idea dies a death asap.
 
I don’t think it’s defeatist. More pragmatic. Instead of putting life on hold pending an unattainable goal we need to immediately start preparing for a future where the virus is endemic. Particularly relevant in Australia right now.

I don't think we should lockdown until we do, or fail to, reach HIT and it will certainly have to be managed as if we won't, at least initially. However, the aim should remain and be pushed hard for this and all major diseases.
 


Israel up to 6k cases/day now. Which is depressing as hell. Boosters seem to be helping though.


Any data available on ITU admissions/severe illness and comparisons vs previous peaks in terms of infections? Wonder if this is down to neutralising antibodies diminishing faster with their dosing interval between the two mRNA doses (compared to the uk).

It would be useful if their booster vaccination programme has the same speed and breadth as their previous national drive and if we can get some useful data on how a booster performs against delta.
 


Israel up to 6k cases/day now. Which is depressing as hell. Boosters seem to be helping though.

Is that data much use to us if we don’t know how many end up in hospital? I wouldn’t get too depressed without knowing that first.
 
Any data available on ITU admissions/severe illness and comparisons vs previous peaks in terms of infections? Wonder if this is down to neutralising antibodies diminishing faster with their dosing interval between the two mRNA doses (compared to the uk).

It would be useful if their booster vaccination programme has the same speed and breadth as their previous national drive and if we can get some useful data on how a booster performs against delta.

From what I can see hospitalisations are on the increase but not at the same rate as previous waves (as you’d expect)

I would be surprised if dosing interval is an issue but you can’t rule it out. It just seems unlikely to me that pushing the second dose out by a few weeks would have much of an effect.

The most likely scenario is that we’re seeing here what we’re seeing everywhere. Reduced vaccine efficacy vs delta. Only this time in a country had such low numbers that they had completely let their guard down by the time delta arrived on the scene. Packed out night clubs, bars etc which hasn’t happened much in the UK despite “freedom day”.

They’ve been firing boosters out just as quick as they did the initial vaccines. Half a million + already.

EDIT: Quick google reveals hospitalisation numbers doubling every 10 days.
 
I’m assuming this is because a lot of adults are vaccinated. You’d expect the proportion of kids getting sick to increase in that scenario.

Kids and covid seems to be the most politicised issue in the US right now. So it’s hard to see the wood for the trees. There also seems to be a big overlap with RSV admissions, which is muddying the waters a bit.

I’m sure @mav_9me know more about this than me though.
The evidence is pointing towards it affecting children now because they obviously aren’t vaccinated. Half of his are under 2 then 5 - 10.
It’s going to be a ahitshow when schools start again
 
"CD24 is a small protein that is anchored to the membrane of the cells and it serves many functions including regulating the mechanism responsible for the cytokine storm. Arber stressed that their treatment, EXO-CD24, does not affect the immune system as a whole, but only targets this specific mechanism, helping find again its correct balance."

https://www.jpost.com/health-scienc...-new-israeli-drug-discharged-in-5-days-675961
 
I’m assuming this is because a lot of adults are vaccinated. You’d expect the proportion of kids getting sick to increase in that scenario.

Kids and covid seems to be the most politicised issue in the US right now. So it’s hard to see the wood for the trees. There also seems to be a big overlap with RSV admissions, which is muddying the waters a bit.

I’m sure @mav_9me know more about this than me though.

Actually I don't. The kids thing is kind of caught in the middle. I obviously follow a bunch of people on Twitter. Half make it a big deal like above, other half point out kids are still doing fine. Like that thing with 20% of hospitalizations being kids. Duh!! Kids are not vaccinated.

My son is 10 y/o and I'm relocating to Florida. Worried for him in school. Not much I can do now.
 
My 14 year old niece has tested positive after going back to school in Atlanta, GA a week ago. Apparently 800 kids have been infected over 3 GA school districts in the week since they went back
 
My friends teenage son and a few of his friends have tested positive and he’s quite sick.
 
My 14 year old niece has tested positive after going back to school in Atlanta, GA a week ago. Apparently 800 kids have been infected over 3 GA school districts in the week since they went back
We start back next Tuesday, and I am very worried about this happening.

2400 people in the building. No mask mandate. No way to maintain social distancing. Maybe only 1/4 or 1/5 of us vaccinated.
My friends teenage son and a few of his friends have tested positive and he’s quite sick.
:(
I hope the come through okay
 
Booked a drive through PCR test for tomorrow. I don't have any of the traditional three symptoms (cough, fever, loss of smell/taste) but do have what feels like a heavy cold. From looking around I see that for the vaccinated that appears to be what symptoms present themselves as. Done a lateral flow that came back negative but considering I'm have a pretty busy week of being in the office and social stuff I figured better safe than sorry.

Results back negative, just a normal cold thank god, means we can get our dishwasher installed this weekend so I don't have to go another week doing it the 'acoustic' way.
 
We start back next Tuesday, and I am very worried about this happening.

2400 people in the building. No mask mandate. No way to maintain social distancing. Maybe only 1/4 or 1/5 of us vaccinated.

:(
I hope the come through okay
I can see why you’re worried. It’s inevitable.
 
Holy shit. That seems insanely low. Is this because most of them are young children?
High schoolers, so 14-18.

I told you, people are simply choosing to not get vaccinated. Only 41% of people in South Carolina are vaccinated and I live & work in one of the politically reddest (and right wing libertarian) parts of it.
 
High schoolers, so 14-18.

I told you, people are simply choosing to not get vaccinated. Only 41% of people in South Carolina are vaccinated and I live & work in one of the reddest parts of it.

Jesus. That 41% figure is shocking. I heard a doc recently talk about “reverse herd immunity”. The idea of herd immunity is that you vaccinate enough people that they protect those who can’t/won’t take a vaccine. So you can indirectly affect the health of others (positively) by taking a vaccine. The flipside would be unvaccinated people keeping the virus so prevalent in the community that they end up affecting the health of the vaccinated (negatively)
 
Actually I don't. The kids thing is kind of caught in the middle. I obviously follow a bunch of people on Twitter. Half make it a big deal like above, other half point out kids are still doing fine. Like that thing with 20% of hospitalizations being kids. Duh!! Kids are not vaccinated.

My son is 10 y/o and I'm relocating to Florida. Worried for him in school. Not much I can do now.
The UK stats are interesting on this. Hospitalisations amongst children rising as Delta cases rise, both numerically and as a percentage of total hospitalisations.
E8YXuOjXMAYW4G2


but hospitalisations v case rate not changing much.

E8YXuOfXsAMSQpp


Again it emphasizes that the vaccines are working in the older age groups. But anyone unvaccinated, including kids, are still at risk - and perhaps higher risk than ever because case rates in those groups are higher than ever.
 
I heard a doc recently talk about “reverse herd immunity”. The idea of herd immunity is that you vaccinate enough people that they protect those who can’t/won’t take a vaccine. So you can indirectly affect the health of others (positively) by taking a vaccine. The flipside would be unvaccinated people keeping the virus so prevalent in the community that they end up affecting the health of the vaccinated (negatively)
Yep. But you try and tell these vaccine refusers that and they’ll laugh at you, tell you to do your own research, and call you a sheep.

“the media is inventing these variants”
— No you moron, you are.

I had to tell a guy who’s currently a history phd candidate yesterday that “this isn’t the fecking flu. My wife intubated 2 people under 30 who had no preexisting conditions” — “oh, well, uh…”
 
Got my best mate's wedding on Monday and one of the groomsmen has just tested positive. I'm best man so I've decided to essentially isolate now until the day.

Proper shit because people are missing once in a lifetime stuff, but what can you do. There will be elderly people there and one of the other groomsmen's wife is heavily pregnant so I'm glad everyone is being sensible.
 
The UK stats are interesting on this. Hospitalisations amongst children rising as Delta cases rise, both numerically and as a percentage of total hospitalisations.
E8YXuOjXMAYW4G2


but hospitalisations v case rate not changing much.

E8YXuOfXsAMSQpp


Again it emphasizes that the vaccines are working in the older age groups. But anyone unvaccinated, including kids, are still at risk - and perhaps higher risk than ever because case rates in those groups are higher than ever.

Interesting data and thankfully seems to have peaked (presumably the impact of school summer holidays)

Although it would certainly support vaccinating the 12-18 y.o’s during the school holidays (which is starting in Ireland this weekend) Health risks aside, the disruption to education at secondary schools could be a nightmare if community transmission is this high (or higher) in September and none of the kids are vaccinated.

The fact this has already been done on a large scale in Israel/US etc gives a bit of extra reassurance too. I wonder if the JCVI might change its stance?
 
I don't see much news about reinfection but this is a pretty horrible story: Chester City FC manager had the virus in November 2020 with mild symptoms and now has had it again less than a year later and has been fighting for his life. The guy is unvaccinated.

https://www.cheshire-live.co.uk/news/chester-cheshire-news/chester-fc-boss-had-shocked-21276264

Even without the vaccine I assumed natural antibodies lasted a bit longer than 9-10 months. Was the guy just unlucky (despite not taking the vaccine)?
 
I don't see much news about reinfection but this is a pretty horrible story: Chester City FC manager had the virus in November 2020 with mild symptoms and now has had it again less than a year later and has been fighting for his life. The guy is unvaccinated.

https://www.cheshire-live.co.uk/news/chester-cheshire-news/chester-fc-boss-had-shocked-21276264

Even without the vaccine I assumed natural antibodies lasted a bit longer than 9-10 months. Was the guy just unlucky (despite not taking the vaccine)?

He's probably had a different variant this time so was still susceptible to it. The vaccines are stronger at protecting against the variants as a whole than the antibody response from getting it for one variant before I think.

It's scary that he's had it twice and the second time has caused him to be fighting for his life.
 
Since almost everyone above the age of 18 in Norway wants to take the vaccine and because other countries have sent us some of their "leftovers"(because they can't get people to use them), we are several weeks ahead of schedule. In the capital roughly 90% have gotten at least one doze. I reckon more than 90% will be fully vaccinated before the middle of October. Almost everyone on Phizer/Moderna.

It's a shame that the vaccines aren't distributed more fairly on a global scale, but since that is the reality we live in I'm happy to at least see that Norway is doing well and that so few here refuse to take the vaccine.
 
I don't see much news about reinfection but this is a pretty horrible story: Chester City FC manager had the virus in November 2020 with mild symptoms and now has had it again less than a year later and has been fighting for his life. The guy is unvaccinated.

https://www.cheshire-live.co.uk/news/chester-cheshire-news/chester-fc-boss-had-shocked-21276264

Even without the vaccine I assumed natural antibodies lasted a bit longer than 9-10 months. Was the guy just unlucky (despite not taking the vaccine)?

There’s a bit of doubt about how well protected you are after an initial mild illness. Anecdotes like this increase those doubts. You do seem to get better protection with the vaccine than you get after a mild dose of covid.
 
Last edited: