One thing's for certain, we're not going to win this tie by playing like we did in Germany.
After careful thought going for this:
-----------------------VDS---------------------
Rafael----------Rio--------Vidic------------Evra
Valencia-------Carrick-------Fletcher-------Nani
------------------Berbatov--------------------
------------------Macheda--------------------
Subs; Kuszczak, Evans, O'Shea, Neville, Giggs, Gibson, Obertan
Rafa in for Neville, give some fight to our attack which we will need and he's fast enough to cope reasonably well with the pace of Ribery. I know he's young but he's a fighter. His persistance also be a bit of a nuisance to the opposition too. Valencia will have to give him a hand defensively.
Reluctantly put Macheda in, not that I don't rate him, but he's young and inexperienced. Plus side is that he's also a bit of a nuisance to defenders when he has the ball, mainly because he's big and fast, but he'll pull defenders away that's for sure. Right ball in at the right time and he could get it in the net.
Put Berbatov there because his ball control and possession will help the midfield, he's also the right one to provide neat, defence splitting little through balls for Macheda. Those two seemed to work well in pre-season. Nani and Valencia can provide the crosses for both of them.